Dr. Sergio Paradiso
Participation year
Project title

The Blood Supply of the Human Insula

The insula is a cortical structure within the brain that lies buried underneath portions of the frontal, temporal, and parietal lobes. Functional imaging studies have implicated it in a number of different brain functions, including addiction, emotion, visceral pain, and olfaction. Due to the deep location of the insula within the brain, the most common method of studying it is via functional imaging. Imaging studies recently have attempted to subdivide the insula to better delineate functional differences. The most widely accepted anatomical division of the insula is into anterior and posterior parts, with the separation marked by the central sulcus of the insula (CIS). Imaging studies use the CIS as a landmark for attributing function to anterior or posterior parts of the insula. However, the CIS does not appear to define a transition in cytoarchitecture and hence is a questionable marker of a functional division. The current research aims to examine whether the microvasculature of the region is in line with this gross morphological division or reflects the underlying cytoarchitecture.
Tonia  Tiewul
Hunter College