HIV, human immunodeficiency virus can possibly lead to acquired immunodeficiency syndrome (AIDS). It impacts the health of people's daily life. HIV/AIDS remains a great challenge to all the ethnic groups and nations. For example, African Americans are hit the hardest, according to Center of Disease Control (CDC), making up 49% of HIV/AIDS victims.

Scientists have begun to explore nanotechnology for developing innovative solutions. Among many nanomedicine applications, silver nanoparticles have proven to be toxic to bacteria, fungi, algae, and viruses. However, one of the disadvantages of using silver nanoparticles is that it is also toxic to normal cells. How to avoid or reduce this negative side-effect must be seriously considered before clinical trials.

In addition, based on recent reports, nanorobots have been introudced in cancer therapy. Nanorobots can be applied in chemotherapy to combat cancer through superior chemical dosage administration. A similar approach is taken to enable nanorobots to deliver anti-HIV drugs.

In this preliminary study of the nanorobots principles, a hybrid method is proposed, by combining the use of RNase L, Tre enzymes and nanorobots, as a possible cure for the virus, instead of the silver nanoparticles because are toxic to not just the virus but healthy cells and because in order to properly bind to the virus they must be between 1-10nm. The only problem with this is that the nanorobots have not been fabricated yet.

In using nanorobots we hope to be able to develop more effective drug therapy methods for HIV patients.  In doing so we hope to extend the patient's life and possibly cure this virus that is not just a burden all over the world.