Chris Pigge, PhD
Synthetic methods for complex molecule construction
Our lab is focused on developing new synthetic sequences that can be used to construct pharmacologically relevant organic molecules. We are particularly interested in concise preparation of heterocyclic ring systems structurally related to those found in various biologically active alkaloid natural products.
Undergraduate major in chemistry or chemistry-related discipline. Completion of introductory organic chemistry lecture and laboratory courses would be beneficial.
Undergraduate researchers will be involved in the synthesis and characterization of heterocyclic precursors. Undergraduate assistants will also evaluate the effectiveness of new cyclization reactions leading to polycyclic ring systems. Research participants will gain hands-on experience in laboratory techniques used in synthetic organic chemistry, including column chromatography, recrystallization, distillation, gas chromatography, HPLC, mass spectrometry, and NMR spectroscopy.