Dr. Charles Grose
Participation year
Project title

Identification of Viral Surface Proteins by Different Imaging Technologies

Surface viral proteins are visualized to investigate their location, prevalence and size. These are important viral protein characteristics because they can illuminate viral protein functions. Varicella-zoster virus, which causes chickenpox and shingles, has proteins that can be visualized by different technologies. The virus has glycoproteins on its surface that have functions which include fusion, egress, and attachment. This project examines different technologies used to view viral surface proteins to determine which is most effective at detecting the presence of Varicella-zoster virus glycoproteins. Three different viral protein visualization techniques were used; fluorescent confocal microscopy, scanning electron microscopy, and western blot.
Clarissa  Brown
University of Central Missouri