Mentor
Dr. M. L. Raghavan
Participation year
2005
Project title

Study of the Effect of Storage Technique on the Mechanical Properties of the Porcine Aorta

Abstract

In the United States 15,000 deaths are attributed to abdominal aortic aneurysm (AAA) every year. About five to seven percent of people over the age of 60 will develop an AAA in the United States. Thus, nowadays a tremendous effort is underway for the search of a treatment to this localized, pathological, blood-filled dilatation of a blood vessel caused by a disease or weakening of the vessel's wall. This research focuses on the measurement of the mechanical properties of a pig aorta. The main goal is to measure how the mechanical properties of the aorta are affected after frozen for 30 days. This question is important because often, studies on mechanical properties may not be possible immediately after harvest, that freezing has on these properties. In order to study the ability of the blood vessel (aorta) to resist deformation of uni-axial extension, mechanical test was performed on 10 specimens from the aorta of an adult pig. The relevance of this research project will be to have a better understanding of how the biological tissues are affected after exposure to frozen temperatures (-20 ∞C), such as what happens with the organ donation.

Lisandra  Colon Jimenez
Education
University of Puerto Rico at Mayaguez